Roles of bovine Waddlia chondrophila and Chlamydia trachomatis in human preterm birth

D Baud; G Goy; S Vasilevsky; M-C Osterheld; M Roth-Kleiner; A Croxatto; G Greub

doi:10.1016/j.nmni.2014.11.004

Roles of bovine Waddlia chondrophila and Chlamydia trachomatis in human preterm birth

New Microbes New Infect. 2014 Nov 29:3:41-5. doi: 10.1016/j.nmni.2014.11.004. eCollection 2015 Jan.

Authors

D Baud¹, G Goy², S Vasilevsky¹, M-C Osterheld³, M Roth-Kleiner⁴, A Croxatto², G Greub⁵

Affiliations

¹ Center for Research on Intracellular Bacteria, Institute of Microbiology, Faculty of Biology and Medicine, University of Lausanne and University Hospital, Lausanne, Switzerland ; Materno-fetal and Obstetrics Research Unit, Department of Obstetrics and Gynaecology, Maternity, University Hospital, Lausanne, Switzerland.
² Center for Research on Intracellular Bacteria, Institute of Microbiology, Faculty of Biology and Medicine, University of Lausanne and University Hospital, Lausanne, Switzerland.
³ Institute of Pathology, University Hospital, Lausanne, Switzerland.
⁴ Clinic of Neonatology, University Hospital, Lausanne, Switzerland.
⁵ Center for Research on Intracellular Bacteria, Institute of Microbiology, Faculty of Biology and Medicine, University of Lausanne and University Hospital, Lausanne, Switzerland ; Infectious Disease Service, University Hospital, Lausanne, Switzerland.

Abstract

Waddlia chondrophila and Chlamydia trachomatis are intracellular bacteria associated with human miscarriage. We investigated their role in human preterm birth. Whereas presence of Chlamydia trachomatis DNA in genital tract was associated with human preterm birth, Waddlia was not, despite being present in women's genital tracts.

Keywords: Adverse pregnancy outcome; Chlamydia-like; genital tract infection; intracellular bacteria; preterm birth.