Distinct localized reentrant drivers in persistent atrial fibrillation identified by noninvasive mapping: relation to f-wave morphology

Han S Lim; Nicolas Derval; Arnaud Denis; Stephan Zellerhoff; Michel Haissaguerre

doi:10.1016/j.ccep.2014.11.008

Distinct localized reentrant drivers in persistent atrial fibrillation identified by noninvasive mapping: relation to f-wave morphology

Card Electrophysiol Clin. 2015 Mar;7(1):153-5. doi: 10.1016/j.ccep.2014.11.008. Epub 2014 Dec 12.

Authors

Han S Lim¹, Nicolas Derval¹, Arnaud Denis¹, Stephan Zellerhoff¹, Michel Haissaguerre²

Affiliations

¹ IHU LIRYC, Electrophysiology and Heart Modeling Institute, Fondation Bordeaux Université, Bordeaux, France.
² IHU LIRYC, Electrophysiology and Heart Modeling Institute, Fondation Bordeaux Université, Bordeaux, France. Electronic address: michel.haissaguerre@chu-bordeaux.fr.

PMID: 25784030
DOI: 10.1016/j.ccep.2014.11.008

Abstract

Noninvasive mapping overcomes previous barriers to provide panoramic beat-to-beat mapping during atrial fibrillation (AF). This article demonstrates the utility of noninvasive mapping in identifying localized driving sources in persistent AF. Reentrant driver activity detected by noninvasive mapping from specific regions correlated with distinct f-wave morphologies. Ablation targeting these drivers resulted in progressive AF cycle length prolongation and termination of the arrhythmia.

Keywords: Catheter ablation; Localized drivers; Noninvasive mapping; Persistent atrial fibrillation; f-wave morphology.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Atrial Fibrillation* / diagnosis
Atrial Fibrillation* / physiopathology
Atrial Fibrillation* / surgery
Catheter Ablation
Electrocardiography / methods*
Electrophysiologic Techniques, Cardiac / methods*
Humans
Imaging, Three-Dimensional
Male