Mycobacterium abscessus pulmonary infection complicated with vertebral osteomyelitis in a heart transplant recipient: case report and literature review

Transpl Infect Dis. 2015 Jun;17(3):418-23. doi: 10.1111/tid.12381. Epub 2015 May 19.

Abstract

Infections produced by Mycobacterium abscessus are emerging in immunosuppressed patients, such as solid organ transplant recipients. We report the first case, to our knowledge, of a vertebral osteomyelitis caused by M. abscessus in a heart transplant recipient, and review the risk factors, manifestations, and therapeutic approaches to this uncommon disease.

Keywords: Mycobacterium abscessus; orthotopic heart transplantation; vertebral osteomyelitis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Clarithromycin / therapeutic use
  • Female
  • Heart Transplantation / adverse effects*
  • Humans
  • Immunocompromised Host
  • Mycobacterium / classification
  • Mycobacterium / isolation & purification*
  • Osteomyelitis / complications*
  • Osteomyelitis / diagnostic imaging
  • Osteomyelitis / drug therapy
  • Osteomyelitis / microbiology
  • Respiratory Tract Infections / complications*
  • Respiratory Tract Infections / diagnostic imaging
  • Respiratory Tract Infections / drug therapy
  • Respiratory Tract Infections / microbiology
  • Risk Factors
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Clarithromycin