A Facile One-Pot Synthesis of a Two-Dimensional MoS2 /Bi2S3 Composite Theranostic Nanosystem for Multi-Modality Tumor Imaging and Therapy

Adv Mater. 2015 May 6;27(17):2775-82. doi: 10.1002/adma.201500870. Epub 2015 Mar 27.

Abstract

2D PEG-ylated MoS2/Bi2 S3 composite nanosheets are successfully constructed by introducing bismuth ions to react with the two extra S atoms in a (NH4)2 MoS4 molecule precursor for solvothermal synthesis of MoS2. The MBP nanosheets can serve as a promising platform for computed tomography and photoacoustic-imaging-guided tumor diagnosis, as well as combined tumor photothermal therapy and sensitized radiotherapy.

Keywords: cancer research; composite materials; imaging; nanomaterials; synergistic therapy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bismuth / chemistry*
  • Cell Line, Tumor
  • Contrast Media / chemistry
  • Contrast Media / metabolism
  • Disulfides / chemistry*
  • Humans
  • Infrared Rays
  • Mice
  • Mice, Nude
  • Molybdenum / chemistry*
  • Nanostructures / chemistry*
  • Nanostructures / therapeutic use
  • Neoplasms / diagnosis*
  • Neoplasms / mortality
  • Neoplasms / therapy
  • Phototherapy
  • Polyethylene Glycols / chemistry
  • Sulfides / chemistry*
  • Survival Rate
  • Theranostic Nanomedicine*
  • Tissue Distribution
  • Tomography, X-Ray Computed

Substances

  • Contrast Media
  • Disulfides
  • Sulfides
  • Polyethylene Glycols
  • Molybdenum
  • Bismuth
  • bismuth sulfide
  • molybdenum disulfide