Purpose: To establish animal model with peri-implantitis after immediate implantation and study bone defect characteristics by Micro-CT.
Methods: Implants were immediately planted in the first mandibular anterior tooth of 12 rabbits. Silk ligatures were placed around one side of the implants to induce peri-implantitis. Micro-CT was used to evaluate bone defect at different periods after implantation.
Results: Silk ligatures around the implants were effective to induce peri-implantitis. With the development of peri-implantitis, implants can not be well integrated with bone. Bone defect was gradually produced and then aggravated, and finally formed typical "V-type" bone defect.
Conclusions: The establishment of animal model with peri-implantitis is simple and effective, which provides important references for relative studies in the field of peri-implantitis.