Chordoma and chondrosarcoma

Jamie J Van Gompel; Jeffrey R Janus

doi:10.1016/j.otc.2015.02.009

Chordoma and chondrosarcoma

Otolaryngol Clin North Am. 2015 Jun;48(3):501-14. doi: 10.1016/j.otc.2015.02.009. Epub 2015 Apr 9.

Authors

Jamie J Van Gompel¹, Jeffrey R Janus²

Affiliations

¹ Departments of Neurosurgery and Otolaryngology, Mayo Clinic, 200 First Street, Southwest, Rochester, MN 55905, USA. Electronic address: vangompel.jamie@mayo.edu.
² Division of Otolaryngology Head and Neck Surgery, Department of Otolaryngology, Mayo Clinic, Rochester, MN 55905, USA.

PMID: 25863568
DOI: 10.1016/j.otc.2015.02.009

Abstract

Chordoma and chondrosarcoma represent 2 fundamentally different and challenging central skull base pathologies. Both are largely surgical diseases with varying outcomes based on completeness of resection. Adjuvant therapy is controversial, although radiation therapy is commonly employed postoperatively, and stereotactic radiosurgery is used either in primary management or treatment of local progression.

Keywords: Chondrosarcoma; Chordoma; Outcome; Proton beam; Surgery.

Publication types

Review
Video-Audio Media

MeSH terms

Chondrosarcoma / surgery*
Chordoma / surgery*
Combined Modality Therapy
Disease Progression
Drug Therapy / methods*
Humans
Magnetic Resonance Imaging
Radiosurgery / methods*
Skull Base Neoplasms / surgery*