[The course of 203 superficial urothelial malignant tumors of the bladder during conservative treatment]

Ann Urol (Paris). 1989;23(4):269-74.
[Article in French]

Abstract

The authors present a total of 203 patients with histologically proven superficial bladder transitional cell cancer. Patients without recurrence had a follow-up longer than 12 months. The mean follow-up from the time of diagnosis was 35 months +/- 27 (standard deviation). Transurethral resection was not systematically followed by intravesical therapy. The following drugs were used: thiotepa, doxorubicin, BCG and rarely mitomycin C. Although BCG was generally used after failure of thiotepa or doxorubicin, it achieved the best results. 13 patients had a total cystectomy (6.4%). Patients without complete remission had a higher percentage of high grade and stage T1 tumors than patients without recurrence (the difference was statistically significant). The same applied to mortality: it was statistically more frequent in the first group than in the second group of patients.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Antineoplastic Agents / therapeutic use*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / epidemiology*
  • Neoplasm Staging
  • Retrospective Studies
  • Urinary Bladder Neoplasms / drug therapy*
  • Urinary Bladder Neoplasms / pathology

Substances

  • Antineoplastic Agents