Improved outcomes of feeding low birth weight infants with predominantly raw human milk versus donor banked milk and formula

J Matern Fetal Neonatal Med. 2016;29(7):1131-8. doi: 10.3109/14767058.2015.1038232. Epub 2015 Apr 24.

Abstract

Objectives: To investigate the benefits of treating low birth weight infants predominantly with mother's own raw milk and early initiation of breastfeeding (raw human milk/breast-fed infants), in comparison to feeding only with donor banked milk (until the third week of life) and afterwards a preterm formula until hospital discharge (donor banked/formula-fed infants).

Methods: One hundred and ninety-two predominantly raw human milk-fed infants (70% of raw and 30% of donor milk) were matched to 192 donor/formula-fed ones (on 1:1 ratio). Aggressive nutrition policy and targeted fortification of human milk were implemented in both groups.

Results: The two groups show similar demographic and perinatal characteristics. Predominantly raw milk-fed infants regained earlier their birth weight, suffered less episodes of feeding intolerance and presented a higher body length and head circumference at discharge (p < 0.001). Those treated mainly with their mothers' milk were able to initiate breastfeeding almost 2 weeks earlier compared to those fed with donor milk who achieved to be bottle-fed later on post-conceptual age (p < 0.001). Infants being breastfed until the 8th month of life conducted less visits for a viral infection to a pediatrician compared to those in the other group (p < 0.001).

Conclusions: Feeding predominantly with mother's raw milk seems to result in optimal neonatal outcomes.

Keywords: Breastfeeding; breast milk; donor banked; formula; raw milk.

MeSH terms

  • Breast Feeding* / statistics & numerical data
  • Case-Control Studies
  • Female
  • Humans
  • Infant Formula
  • Infant Nutritional Physiological Phenomena*
  • Infant, Low Birth Weight / physiology*
  • Infant, Newborn
  • Infant, Premature / physiology
  • Intensive Care Units, Neonatal / statistics & numerical data
  • Length of Stay / statistics & numerical data
  • Male
  • Milk Banks*
  • Milk, Human*
  • Mothers
  • Patient Discharge / statistics & numerical data
  • Preservation, Biological / standards
  • Prognosis