Infantile Hemangioma: Clinical Characteristics and Efficacy of Treatment with the Long-Pulsed 1,064-nm Neodymium-Doped Yttrium Aluminum Garnet Laser in 794 Chinese Patients

Pediatr Dermatol. 2015 Jul-Aug;32(4):495-500. doi: 10.1111/pde.12593. Epub 2015 May 7.

Abstract

Objective: This study aimed to evaluate the clinical characteristics of infantile hemangiomas (IHs) and the safety and efficacy of the long-pulse 1,064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser for definitive treatment of IHs in 794 Chinese patients.

Methods: Infants with hemangiomas who had received long-pulse 1,064-nm Nd:YAG laser treatment in our department in the last 5 years were recruited. Demographic and clinical characteristics were recorded and outcomes of long-pulse 1,064-nm Nd:YAG laser treatment were assessed. Statistical analyses were performed to identify factors that affected the efficacy of treatment.

Results: The efficacy of long-pulse 1,064-nm Nd:YAG laser for the treatment of IHs in all patients in our study was 87.57%. Efficacy did not depend on sex or the location of the lesion. Older age and superficial hemangioma were the primary factors contributing to greater efficacy of long-pulse 1,064-nm Nd:YAG laser treatment for IHs. The most common side effects were pigment changes, skin atrophy, and wrinkled redundant skin, which usually resolved spontaneously within 1 to 3 years.

Conclusions: Long-pulse 1,064-nm Nd:YAG laser is a safe and efficacious treatment for IHs.

MeSH terms

  • Female
  • Hemangioma, Capillary / radiotherapy*
  • Humans
  • Infant
  • Infant, Newborn
  • Laser Therapy / methods*
  • Lasers, Solid-State*
  • Male
  • Skin Neoplasms / radiotherapy*
  • Treatment Outcome