Myocardial scintigraphy with the use of 201-thallium was performed in 92 female patients aged 38 to 87 years (initially and after 24 hours). The menstrual cycle phases were revealed to influence perfusion and metabolism of the myocardium in women with the normal ovarian cycle which should be taken into consideration in the interpretation of scintigrams in young women. The results of examining elderly persons with a long menopause have demonstrated excess saturation of scintigrams, both initial and long-term, which is primarily determined by changes in the coronary bed by the three-vascular injury type and hypertrophy of the left ventricle myocardium.