Draft Genome Sequences of Four NDM-1-Producing Klebsiella pneumoniae Strains from a Health Care Facility in Northern California

Alexander L Greninger; Ilya Chorny; Susan Knowles; Valerie L Ng; Vishnu Chaturvedi

doi:10.1128/genomeA.00421-15

Draft Genome Sequences of Four NDM-1-Producing Klebsiella pneumoniae Strains from a Health Care Facility in Northern California

Genome Announc. 2015 May 14;3(3):e00421-15. doi: 10.1128/genomeA.00421-15.

Authors

Alexander L Greninger¹, Ilya Chorny², Susan Knowles², Valerie L Ng³, Vishnu Chaturvedi⁴

Affiliations

¹ Microbial Diseases Laboratory, California Department of Public Health, Richmond, California, USA.
² Illumina, Inc., San Diego, California, USA.
³ Department of Laboratory Medicine and Pathology, Alameda County Medical Center, Oakland, California, USA.
⁴ Microbial Diseases Laboratory, California Department of Public Health, Richmond, California, USA vishnu.chaturvedi@cdph.ca.gov.

Abstract

We report the draft genome sequences of Klebsiella pneumoniae strains from four patients at a northern California health care facility. All strains contained the New Delhi metallo-β-lactamase (NDM1) carbapenemase with extended antibiotic resistance, including resistance to expanded-spectrum cephalosporins, imipenem, ertapenem, and meropenem. NDM gene alignments revealed that the resistance was plasmid encoded.