The importance of upper gastrointestinal endoscopy in morbidly obese patients

Turk J Gastroenterol. 2015 May;26(3):228-31. doi: 10.5152/tjg.2015.0083.

Abstract

Background/aims: Obesity is an epidemic and its prevalence and number of patients underwent bariatric surgery continue to increase worldwide. This study aimed to evaluate endoscopic findings and co-morbidities, to investigate the prevalence of Helicobacter pylori (H. pylori) infection and the relationship between body mass index (BMI) and gastroesophageal sphincter incompetency in obese patients.

Materials and methods: An upper gastrointestinal system endoscopy and mucosal sampling were performed in all patients hospitalized for bariatric surgery. Age, gender, BMI, co-morbidities and endoscopic findings were recorded. Gastroesophageal sphincter incompetency was classified according to Hill classification. The patients were divided into two groups: group I, endoscopically normal and group II, endoscopically abnormal.

Results: Total 127 patients were enrolled into prospective study. Of these, 93 (%73.2) were female and the mean age was 38.9±12.5 years (range: 16-68). Abnormal endoscopic findings and H. pylori were detected in 80.4% and 44.9% of patients, respectively. In group II, patients were older, BMI higher and H. pylori more prevalent (all statistically significant). Diabetes mellitus, hypertension and dyslipidemia were the most frequent common co-morbidities. Rate of multiple co-morbidities were more common in group II. Gastroesophageal sphincter incompetency in total group was observed in a rate of 46.5% and was weakly correlated with BMI.

Conclusion: Four-fifths of obese patients have at least one endoscopic abnormal finding, three fourth at least one co-morbidity and half H. pylori positivity. Upper gastrointestinal system endoscopy should be performed routinely in all patients to predict and prevent complications following bariatric surgery.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Bariatric Surgery
  • Body Mass Index
  • Comorbidity
  • Diabetes Mellitus / epidemiology
  • Diabetes Mellitus / pathology
  • Dyslipidemias / epidemiology
  • Dyslipidemias / pathology
  • Endoscopy, Gastrointestinal / methods*
  • Endoscopy, Gastrointestinal / statistics & numerical data
  • Esophageal Sphincter, Lower / physiopathology*
  • Female
  • Gastric Mucosa / microbiology
  • Helicobacter Infections / epidemiology*
  • Helicobacter Infections / microbiology
  • Helicobacter pylori / isolation & purification
  • Humans
  • Hypertension / epidemiology
  • Hypertension / pathology
  • Male
  • Middle Aged
  • Obesity, Morbid / complications*
  • Obesity, Morbid / microbiology
  • Obesity, Morbid / surgery
  • Preoperative Care / methods
  • Preoperative Care / statistics & numerical data*
  • Prevalence
  • Prospective Studies
  • Young Adult