Peripheral late reactivation of a previously typical monofocal Baló's concentric sclerosis lesion

Mult Scler. 2015 Jul;21(8):1080-3. doi: 10.1177/1352458515586087. Epub 2015 May 26.

Abstract

We report a 41-year-old woman with rapidly progressive left hemiparesis, revealing an inflammatory reactivation of a previously known parietal Baló's concentric sclerosis lesion. The first attack occurred five years before. After a slow recovery following high-dose steroid infusions the patient stabilized. Because of recurrent ataxia and left hemiparesis a new magnetic resonance imaging was performed showing an extension of the initial lesion with a peripheral gadolinium enhancement on T1-weighted images. Such a reactivation pattern of an isolated Baló's concentric sclerosis lesion, occurring some years later, is described for the first time.

Keywords: Baló’s concentric sclerosis lesion; Left hemiparesis; inflammatory reactivation; magnetic resonance imaging.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Inflammatory Agents / therapeutic use
  • Diffuse Cerebral Sclerosis of Schilder / complications
  • Diffuse Cerebral Sclerosis of Schilder / drug therapy
  • Diffuse Cerebral Sclerosis of Schilder / pathology*
  • Female
  • Humans
  • Immunoglobulin G / cerebrospinal fluid
  • Inflammation / etiology
  • Inflammation / pathology
  • Magnetic Resonance Imaging
  • Paresis / etiology
  • Steroids / therapeutic use

Substances

  • Anti-Inflammatory Agents
  • Immunoglobulin G
  • Steroids