A cardiorenal-pulmonary-cutaneous-muscle syndrome

Clin Kidney J. 2013 Apr;6(2):199-200. doi: 10.1093/ckj/sft017.

Abstract

Anti-synthetase syndrome is a relatively recently described auto-immune disease characterized by auto-antibodies to enzymes that acetylate transfer RNA (tRNA). Interstitial pulmonary disease and inflammatory myopathy are regular findings. Our patient also exhibited a lupus-like glomerulonephritis. An important clue was the presence of 'mechanics' hands. Nephrologists need to be aware of this syndrome.

Keywords: anti-synthetase syndrome; interstitial lung disease; lupus nephritis; mechanics hands.