Predictability of capsule endoscopy referred to a tertiary care center for double-balloon enteroscopy

Eur J Gastroenterol Hepatol. 2015 Sep;27(9):1052-6. doi: 10.1097/MEG.0000000000000401.

Abstract

Objectives: Patients with obscure gastrointestinal bleeding with 'positive' findings on video capsule endoscopy (VCE) by gastroenterologists practicing in the community are often referred to tertiary care centers for double-balloon enteroscopy (DBE). Our study explores the degree of concordance between these two procedures performed in two different clinical settings.

Methods: Concordance between the procedures was estimated using a κ-coefficient.

Results: A total of 73 patients with obscure gastrointestinal bleeding were referred to our center for DBE after undergoing VCE elsewhere. Ten of these patients (10/73 or 13.7%) had been found to have bleeding in the small bowel on VCE without any concrete diagnosis. DBE revealed the source of bleeding in 17 of the 22 patients (77.3%) with normal VCE. The referral diagnosis was correct in 31 cases (31/73 or 42.5%). The κ-coefficient for VCE and DBE for the 63 patients was 0.28, suggesting poor agreement between the two procedures. However, most patients with a referral diagnosis of vascular pathology were confirmed to have vascular disease on DBE (19/23 or 82.6%).

Conclusion: Our study shows that there is a poor concordance between capsule endoscopy performed in the community and confirmatory DBE performed at our tertiary care center.

Publication types

  • Comparative Study

MeSH terms

  • Capsule Endoscopy*
  • Community Health Services*
  • Double-Balloon Enteroscopy*
  • Female
  • Gastrointestinal Hemorrhage / diagnosis*
  • Gastrointestinal Hemorrhage / etiology
  • Gastrointestinal Hemorrhage / pathology
  • Gastrointestinal Tract / pathology*
  • Humans
  • Male
  • Observer Variation
  • Predictive Value of Tests
  • Prospective Studies
  • Referral and Consultation*
  • Reproducibility of Results
  • Tertiary Care Centers*