Comparative analysis of Laparoscopic versus open surgical radiofrequency ablation for malignant liver tumors

Korean J Hepatobiliary Pancreat Surg. 2014 Nov;18(4):122-8. doi: 10.14701/kjhbps.2014.18.4.122. Epub 2014 Nov 30.

Abstract

Backgrounds/aims: This study aims to evaluate the comparative effectiveness of two surgical approaches on the treatment outcomes of radiofrequency ablation (RFA) for malignant liver tumors.

Methods: Fifty-seven patients with malignant liver tumors, hepatocellular carcinoma, cholangiocarcinoma and liver metastases, who were candidates for RFA, underwent laparoscopic or open surgical treatments.

Results: The patients' characteristics were comparable in the two groups that received open (n=33, 57.9%) and laparoscopic (n=24, 42.1%) surgical treatments. There were no statistically significant differences between the two groups in terms of recurrence rate (p=0.337) and overall survival (p=0.423). However, patients in the laparoscopic RFA group had significantly shorter hospital stay (14.1 vs. 5.9 days, p<0.05) and experienced fewer complications (Grade I: 62.5% vs. 26.3%, p=0.102).

Conclusions: Laparoscopic RFA can be performed for malignant liver tumors with lower morbidity rates, less invasiveness and lower expense compared to open surgical approach.

Keywords: Cholangiocarcinoma; Hepatocellular carcinoma; Liver metastasis; Malignant liver tumor; Radiofrequency ablation.