PTHrP-Induced Refractory Malignant Hypercalcemia in a Patient With Chronic Lymphocytic Leukemia Responding to Denosumab

Clin Lymphoma Myeloma Leuk. 2015 Sep;15(9):e137-40. doi: 10.1016/j.clml.2015.06.007. Epub 2015 Jun 19.
No abstract available

Keywords: CLL; Denosumab; Humoral hypercalcemia; Hypercalcemia of malignancy; PTHrP; Parathyroid hormone–related protein.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Denosumab / therapeutic use*
  • Humans
  • Hypercalcemia / drug therapy*
  • Hypercalcemia / metabolism*
  • Hypercalcemia / pathology
  • Leukemia, Lymphocytic, Chronic, B-Cell / metabolism*
  • Leukemia, Lymphocytic, Chronic, B-Cell / pathology
  • Male
  • Paraneoplastic Syndromes / drug therapy*
  • Paraneoplastic Syndromes / metabolism*
  • Paraneoplastic Syndromes / pathology
  • Parathyroid Hormone-Related Protein / metabolism*

Substances

  • Parathyroid Hormone-Related Protein
  • Denosumab

Supplementary concepts

  • Humoral Hypercalcemia Of Malignancy