Hypoxanthine accumulation and dopamine depletion in Lesch-Nyhan disease

Adv Exp Med Biol. 1989:253A:165-72. doi: 10.1007/978-1-4684-5673-8_27.
No abstract available

MeSH terms

  • Adenosine / analogs & derivatives
  • Adenosine / pharmacology
  • Adenosine-5'-(N-ethylcarboxamide)
  • Animals
  • Apomorphine / antagonists & inhibitors
  • Brain / metabolism*
  • Dopamine / analogs & derivatives
  • Dopamine / metabolism*
  • Hypoxanthines / metabolism*
  • Lesch-Nyhan Syndrome / metabolism*
  • Male
  • Rats
  • Rats, Inbred Strains
  • Trigeminal Caudal Nucleus / metabolism

Substances

  • Hypoxanthines
  • Adenosine-5'-(N-ethylcarboxamide)
  • Adenosine
  • Apomorphine
  • Dopamine