Laboratory Investigation of the First Case of Botulism Caused by Clostridium butyricum Type E Toxin in the United States

Janet K Dykes; Carolina Lúquez; Brian H Raphael; Loretta McCroskey; Susan E Maslanka

doi:10.1128/JCM.01351-15

Laboratory Investigation of the First Case of Botulism Caused by Clostridium butyricum Type E Toxin in the United States

J Clin Microbiol. 2015 Oct;53(10):3363-5. doi: 10.1128/JCM.01351-15. Epub 2015 Aug 5.

Authors

Janet K Dykes¹, Carolina Lúquez², Brian H Raphael², Loretta McCroskey², Susan E Maslanka²

Affiliations

¹ Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA jdykes@cdc.gov.
² Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Abstract

We report here the laboratory investigation of the first known case of botulism in the United States caused by Clostridium butyricum type E. This investigation demonstrates the importance of extensive microbiological examination of specimens, which resulted in the isolation of this organism.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Botulinum Toxins / analysis*
Botulism / diagnosis*
Botulism / microbiology*
Clostridium butyricum / classification
Clostridium butyricum / genetics
Clostridium butyricum / isolation & purification*
Cluster Analysis
DNA, Bacterial / chemistry
DNA, Bacterial / genetics
Electrophoresis, Gel, Pulsed-Field
Feces / microbiology
Humans
Infant, Newborn
Molecular Sequence Data
Molecular Typing
Phylogeny
Sequence Analysis, DNA
Sequence Homology
United States

Substances

DNA, Bacterial
Botulinum Toxins
botulinum toxin type E

Associated data

GENBANK/KP455988