Identification of NDM-1 in a Putatively Novel Acinetobacter Species ("NB14") Closely Related to Acinetobacter pittii

Antimicrob Agents Chemother. 2015 Oct;59(10):6657-60. doi: 10.1128/AAC.01455-15. Epub 2015 Aug 10.

Abstract

In this study, we describe the molecular characterization of a plasmid-located blaNDM-1 harbored by an Acinetobacter clinical isolate recovered from a patient in Turkey that putatively constitutes a novel Acinetobacter species, as shown by its distinct ARDRA (amplified 16S ribosomal DNA restriction analysis) profile and molecular sequencing techniques. blaNDM-1 was carried by a conjugative plasmid widespread among non-baumannii Acinetobacter isolates, suggesting its potential for dissemination before reaching more clinically relevant Acinetobacter species.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter / classification
  • Acinetobacter / enzymology*
  • Acinetobacter / genetics*
  • DNA, Ribosomal / genetics
  • Humans
  • Molecular Sequence Data
  • Plasmids / genetics
  • Turkey
  • beta-Lactamases / genetics*

Substances

  • DNA, Ribosomal
  • beta-Lactamases
  • beta-lactamase NDM-1

Associated data

  • GENBANK/KJ600787
  • GENBANK/KJ600788
  • GENBANK/KJ600789
  • GENBANK/KJ600790
  • GENBANK/KJ600791
  • GENBANK/KJ600793
  • GENBANK/KJ600794
  • GENBANK/KM923969