Typhoid Fever Complicated by Hemophagocytic Lymphohistiocytosis and Rhabdomyolysis

Am J Trop Med Hyg. 2015 Nov;93(5):1068-9. doi: 10.4269/ajtmh.15-0385. Epub 2015 Aug 31.

Abstract

Hemophagocytic lymphohistiocytosis (HLH) and rhabdomyolysis are rare complications of typhoid fever from Salmonella enterica serovar Typhi. Herein, we describe the clinical features in a 21-year-old female from India who presented to the intensive care unit with fever, severe pancytopenia, and rhabdomyolysis.

Publication types

  • Case Reports

MeSH terms

  • Disk Diffusion Antimicrobial Tests
  • Drug Combinations
  • Drug Resistance, Bacterial
  • Drug Therapy, Combination
  • Female
  • Fever
  • Humans
  • India
  • Lymphohistiocytosis, Hemophagocytic / complications*
  • Lymphohistiocytosis, Hemophagocytic / drug therapy
  • Rhabdomyolysis / complications*
  • Rhabdomyolysis / drug therapy
  • Salmonella typhi / drug effects
  • Salmonella typhi / isolation & purification*
  • Sepsis
  • Sulfamethizole / therapeutic use
  • Treatment Outcome
  • Trimethoprim / therapeutic use
  • Typhoid Fever / complications*
  • Typhoid Fever / drug therapy
  • Young Adult

Substances

  • Drug Combinations
  • Sulfamethizole
  • trimethoprim sulfamethizole
  • Trimethoprim