Quality Assurance for Antimicrobial Susceptibility Testing of Neisseria gonorrhoeae in Canada, 2003 to 2012

Pam Sawatzky; Gary Liu; Jo-Anne R Dillon; Vanessa Allen; Brigitte Lefebvre; Linda Hoang; Greg Tyrrell; Paul Van Caeseele; Paul Levett; Irene Martin

doi:10.1128/JCM.02303-15

Quality Assurance for Antimicrobial Susceptibility Testing of Neisseria gonorrhoeae in Canada, 2003 to 2012

J Clin Microbiol. 2015 Nov;53(11):3646-9. doi: 10.1128/JCM.02303-15. Epub 2015 Sep 2.

Authors

Affiliations

¹ Bacteriology and Enteric Diseases Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
² University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
³ Public Health Ontario Laboratories, Toronto, Ontario, Canada.
⁴ Laboratoire de Santé Publique du Québec, Ste-Anne-de-Bellevue, Québec, Canada.
⁵ British Columbia Public Health Microbiology and Reference Laboratory, Vancouver, British Columbia, Canada.
⁶ Provincial Laboratory for Public Health, Edmonton, Alberta, Canada.
⁷ Cadham Provincial Laboratory, Winnipeg, Manitoba, Canada.
⁸ Saskatchewan Disease Control Laboratory, Regina, Saskatchewan, Canada.
⁹ Bacteriology and Enteric Diseases Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada irene.martin@phac-aspc.gc.ca.

Abstract

Data from the Canadian National Gonococcal Antimicrobial Susceptibility Comparison Program, including results from 25 proficiency panels distributed between 2003 and 2012, were analyzed. The average MIC agreement between the participating laboratories ranged from 85.6% to 98.8% over the 10-year period, with the interpretation agreement ranging from 85.7% to 98.1%.

MeSH terms

Anti-Bacterial Agents / pharmacology*
Canada
Drug Resistance, Bacterial
Gonorrhea / drug therapy
Microbial Sensitivity Tests / methods*
Neisseria gonorrhoeae / drug effects*
Quality Assurance, Health Care*

Substances

Anti-Bacterial Agents