A Successful Renal Transplantation Case After Stem Cell Transplantation

Transplant Proc. 2015 Sep;47(7):2233-5. doi: 10.1016/j.transproceed.2015.05.012.

Abstract

Renal transplantation is the most effective treatment method for end-stage renal disease (ESRD). However, new treatment modalities are being investigated, such as immunotoleration, to avoid the acute and chronic side effects of immunosuppressant drugs. We report a case in which a man had undergone allogenic stem cell transplantation from his brother 16 years ago due to chronic myeloid leukemia, and who then developed ESRD due to arterial hypertension and underwent renal transplantation (Rtx) from the same brother. The patient was followed up without immunosuppression due to full chimerism.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Immune Tolerance
  • Immunosuppression Therapy / methods*
  • Kidney Failure, Chronic / immunology
  • Kidney Failure, Chronic / surgery*
  • Kidney Transplantation*
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / surgery
  • Living Donors
  • Male
  • Middle Aged
  • Siblings
  • Stem Cell Transplantation*
  • Treatment Outcome