The Function Biomedical Informatics Research Network Data Repository

David B Keator; Theo G M van Erp; Jessica A Turner; Gary H Glover; Bryon A Mueller; Thomas T Liu; James T Voyvodic; Jerod Rasmussen; Vince D Calhoun; Hyo Jong Lee; Arthur W Toga; Sarah McEwen; Judith M Ford; Daniel H Mathalon; Michele Diaz; Daniel S O'Leary; H Jeremy Bockholt; Syam Gadde; Adrian Preda; Cynthia G Wible; Hal S Stern; Aysenil Belger; Gregory McCarthy; Burak Ozyurt; Steven G Potkin; FBIRN

doi:10.1016/j.neuroimage.2015.09.003

The Function Biomedical Informatics Research Network Data Repository

Neuroimage. 2016 Jan 1;124(Pt B):1074-1079. doi: 10.1016/j.neuroimage.2015.09.003. Epub 2015 Sep 11.

Authors

David B Keator¹, Theo G M van Erp², Jessica A Turner³, Gary H Glover⁴, Bryon A Mueller⁵, Thomas T Liu⁶, James T Voyvodic⁷, Jerod Rasmussen², Vince D Calhoun⁸, Hyo Jong Lee⁹, Arthur W Toga¹⁰, Sarah McEwen¹¹, Judith M Ford¹², Daniel H Mathalon¹², Michele Diaz¹³, Daniel S O'Leary¹⁴, H Jeremy Bockholt¹⁵, Syam Gadde⁷, Adrian Preda², Cynthia G Wible¹⁶, Hal S Stern¹⁷, Aysenil Belger¹⁸, Gregory McCarthy¹⁹, Burak Ozyurt²⁰, Steven G Potkin²; FBIRN

Affiliations

¹ Department of Psychiatry and Human Behavior, University of California, Irvine, CA, USA. Electronic address: dbkeator@uci.edu.
² Department of Psychiatry and Human Behavior, University of California, Irvine, CA, USA.
³ Mind Research Network, Albuquerque, NM, USA; Department of Psychiatry and Neuroscience Institute, Georgia State University, Atlanta, GA, USA.
⁴ Department of Radiology, Stanford University, Stanford, CA, USA.
⁵ Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA.
⁶ Center for Functional MRI, University of California, San Diego, CA, USA.
⁷ Brain Imaging and Analysis Center, Duke University Medical Center, Durham, NC, USA.
⁸ Mind Research Network, Albuquerque, NM, USA; Department of ECE, University of New Mexico, Albuquerque, NM, USA; Department of Psychiatry, University of New Mexico, Albuquerque, NM, USA.
⁹ Department of Computer Science and Engineering, Chonbuk National University, Republic of Korea.
¹⁰ Laboratory of Neuro Imaging, University of Southern California, Los Angeles, USA; Institute for Neuroimaging and Informatics, University of Southern California, Los Angeles, USA; Keck School of Medicine of USC, University of Southern California, Los Angeles, USA.
¹¹ Department of Psychology, University of California, Los Angeles, CA, USA.
¹² Department of Psychiatry, University of California, San Francisco, CA, USA; Brain Imaging and EEG Laboratory, University of California, San Francisco, CA, USA; San Francisco VA Medical Center, San Francisco, CA, USA.
¹³ Department of Psychology, Penn State University, University Park, PA, USA.
¹⁴ Department of Psychiatry, University of Iowa, Iowa City, IA, USA.
¹⁵ Department of ECE, University of New Mexico, Albuquerque, NM, USA; Department of Psychiatry, University of Iowa, Iowa City, IA, USA.
¹⁶ Department of Psychiatry, Harvard Medical School, Boston, MA, USA; Brockton VAMC, Boston, MA, USA.
¹⁷ Department of Statistics, University of California, Irvine, CA, USA.
¹⁸ Department of Psychiatry, University of North Carolina at Chapel Hill, NC, USA; Department of Psychology, University of North Carolina at Chapel Hill, NC, USA.
¹⁹ Department of Psychology, Yale University, New Haven, CT, USA.
²⁰ Department of Psychiatry, University of California, San Diego, CA, USA.

Abstract

The Function Biomedical Informatics Research Network (FBIRN) developed methods and tools for conducting multi-scanner functional magnetic resonance imaging (fMRI) studies. Method and tool development were based on two major goals: 1) to assess the major sources of variation in fMRI studies conducted across scanners, including instrumentation, acquisition protocols, challenge tasks, and analysis methods, and 2) to provide a distributed network infrastructure and an associated federated database to host and query large, multi-site, fMRI and clinical data sets. In the process of achieving these goals the FBIRN test bed generated several multi-scanner brain imaging data sets to be shared with the wider scientific community via the BIRN Data Repository (BDR). The FBIRN Phase 1 data set consists of a traveling subject study of 5 healthy subjects, each scanned on 10 different 1.5 to 4 T scanners. The FBIRN Phase 2 and Phase 3 data sets consist of subjects with schizophrenia or schizoaffective disorder along with healthy comparison subjects scanned at multiple sites. In this paper, we provide concise descriptions of FBIRN's multi-scanner brain imaging data sets and details about the BIRN Data Repository instance of the Human Imaging Database (HID) used to publicly share the data.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Adolescent
Adult
Aged
Biomedical Research
Databases, Factual*
Female
Healthy Volunteers
Humans
Information Dissemination
Magnetic Resonance Imaging
Male
Medical Informatics*
Middle Aged
Neuroimaging
Psychotic Disorders / pathology
Reference Values
Research
Schizophrenia / pathology
Young Adult

Abstract

Publication types

MeSH terms

Grants and funding