Revealing the complexity of retroviral repression

Gernot Wolf; Todd S Macfarlan

doi:10.1016/j.cell.2015.09.014

Revealing the complexity of retroviral repression

Cell. 2015 Sep 24;163(1):30-2. doi: 10.1016/j.cell.2015.09.014.

Authors

Gernot Wolf¹, Todd S Macfarlan²

Affiliations

¹ The Eunice Kennedy Shriver National Institute of Child Health and Human Development, The National Institutes of Health, Bethesda, MD 20892, USA.
² The Eunice Kennedy Shriver National Institute of Child Health and Human Development, The National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: todd.macfarlan@nih.gov.

Abstract

Retroviral restriction is a complex phenomenon that, despite remarkable recent progress, is far from being well understood. In this Preview, we introduce an insightful study by Yang et al. that represents the first attempt to identify the global determinants of retroviral repression in pluripotent mammalian cells.

Revealing the complexity of retroviral repression

Authors

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Abstract

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