Genetic manipulation of microglia during brain development and disease

Biochim Biophys Acta. 2016 Mar;1862(3):299-309. doi: 10.1016/j.bbadis.2015.09.019. Epub 2015 Oct 14.
No abstract available

Keywords: CX(3)CR1; Genetic manipulation; Labeling; Microglia; Targeting; Yolk sac.

Publication types

  • Review

MeSH terms

  • Amyotrophic Lateral Sclerosis / genetics
  • Amyotrophic Lateral Sclerosis / metabolism
  • Amyotrophic Lateral Sclerosis / pathology*
  • Animals
  • Animals, Genetically Modified
  • Brain / growth & development*
  • Brain / metabolism
  • Brain / pathology*
  • Disease Models, Animal
  • Gene Targeting / methods
  • Humans
  • Mice
  • Microglia / metabolism
  • Microglia / pathology*
  • Multiple Sclerosis / genetics
  • Multiple Sclerosis / metabolism
  • Multiple Sclerosis / pathology*
  • Parkinson Disease / genetics
  • Parkinson Disease / metabolism
  • Parkinson Disease / pathology*