Acute hepatitis C in the Netherlands: characteristics of the epidemic in 2014

S J Hullegie; G E L van den Berk; E M S Leyten; J E Arends; F N Lauw; J T M van der Meer; D Posthouwer; A van Eeden; P P Koopmans; C Richter; M E E van Kasteren; F P Kroon; W F W Bierman; P H P Groeneveld; K D Lettinga; R Soetekouw; E J G Peters; D W M Verhagen; A I van Sighem; M A A Claassen; B J A Rijnders

doi:10.1016/j.cmi.2015.10.012

Acute hepatitis C in the Netherlands: characteristics of the epidemic in 2014

Clin Microbiol Infect. 2016 Feb;22(2):209.e1-209.e3. doi: 10.1016/j.cmi.2015.10.012. Epub 2015 Oct 17.

Authors

S J Hullegie¹, G E L van den Berk², E M S Leyten³, J E Arends⁴, F N Lauw⁵, J T M van der Meer⁶, D Posthouwer⁷, A van Eeden⁸, P P Koopmans⁹, C Richter¹⁰, M E E van Kasteren¹¹, F P Kroon¹², W F W Bierman¹³, P H P Groeneveld¹⁴, K D Lettinga¹⁵, R Soetekouw¹⁶, E J G Peters¹⁷, D W M Verhagen¹⁸, A I van Sighem¹⁹, M A A Claassen²⁰, B J A Rijnders²⁰

Affiliations

¹ Department of Internal Medicine and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands. Electronic address: b.hullegie@erasmusmc.nl.
² Department of Internal Medicine and Infectious Diseases, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
³ Department of Internal Medicine and Infectious Diseases, Medisch Centrum Haaglanden, Den Haag, The Netherlands.
⁴ Department of Internal Medicine and Infectious Diseases, Universitair Medisch Centrum Utrecht, Utrecht, The Netherlands.
⁵ Department of Internal Medicine and Infectious Diseases, Slotervaart Ziekenhuis, Amsterdam, The Netherlands.
⁶ Department of Internal Medicine and Infectious Diseases, Academisch Medisch Centrum, Amsterdam, The Netherlands.
⁷ Department of Internal Medicine and Infectious Diseases, Maastricht Universitair Medisch Centrum, Maastricht, The Netherlands.
⁸ DC Klinieken, Amsterdam, The Netherlands.
⁹ Department of Internal Medicine and Infectious Diseases, Radboud Universitair Medisch Centrum, Nijmegen, The Netherlands.
¹⁰ Department of Internal Medicine and Infectious Diseases, Rijnstate Ziekenhuis, Arnhem, The Netherlands.
¹¹ Department of Internal Medicine and Infectious Diseases, Elisabeth Ziekenhuis, Tilburg, The Netherlands.
¹² Department of Internal Medicine and Infectious Diseases, Leids Universitair Medisch Centrum, Leiden, The Netherlands.
¹³ Department of Internal Medicine and Infectious Diseases, University of Groningen, Universitair Medisch Centrum Groningen, Groningen, The Netherlands.
¹⁴ Department of Internal Medicine and Infectious Diseases, Isala Klinieken, Zwolle, The Netherlands.
¹⁵ Department of Internal Medicine and Infectious Diseases, Sint Lucas Andreas Ziekenhuis, Amsterdam, The Netherlands.
¹⁶ Department of Internal Medicine and Infectious Diseases, Kennemer Gasthuis, Haarlem, The Netherlands.
¹⁷ Department of Internal Medicine and Infectious Diseases, VU Medisch Centrum, Amsterdam, The Netherlands.
¹⁸ Department of Internal Medicine and Infectious Diseases, Jan van Goyen Kliniek, Amsterdam.
¹⁹ Stichting HIV Monitoring, Amsterdam, The Netherlands.
²⁰ Department of Internal Medicine and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands.

PMID: 26482267
DOI: 10.1016/j.cmi.2015.10.012

Abstract

Within the Dutch Acute HCV in HIV Study, a surveillance system was initiated to estimate the incidence of hepatitis C virus (HCV) infections in 2014. Following the Dutch HIV treatment guidelines, HIV-positive men having sex with men (MSM) in 19 participating centers were screened. Ninety-nine acute HCV infections were reported, which resulted in a mean incidence of 11 per 1000 patient-years of follow-up. Unfortunately, the HCV epidemic among Dutch HIV-positive MSM is not coming to a halt.

Keywords: Acute hepatitis C; HIV; MSM; epidemiology; incidence.

MeSH terms

Adult
Coinfection / epidemiology
Coinfection / virology
Epidemics*
HIV Infections / virology*
Hepatitis C / epidemiology*
Hepatitis C / virology
Homosexuality, Male
Humans
Incidence
Male
Middle Aged
Netherlands / epidemiology
Population Surveillance
Risk Factors