Cyclosporine-associated toxicity in pancreatic islet cells and its prevention by K-MAP in cyclosporine-treated animals

Transplant Proc. 1989 Feb;21(1 Pt 3):2774-9.

Authors

S Teraoka¹, T Kawai, Y Yamaguchi, T Tojinbara, S Fujita, I Nakajima, Y Nakagawa, H Fujikawa, T Hayashi, H Honda, et al.

Affiliation

¹ Department of Surgery, Tokyo Women's Medical College, Japan.

PMID: 2650362

No abstract available

MeSH terms

4-Aminobenzoic Acid / therapeutic use*
Aminobenzoates / therapeutic use*
Animals
Body Weight / drug effects
Cyclosporins / analysis
Cyclosporins / pharmacokinetics
Cyclosporins / toxicity*
Glucose Tolerance Test
Insulin / blood
Islets of Langerhans / drug effects*
Islets of Langerhans / pathology
Islets of Langerhans / ultrastructure
Male
Mannose / analogs & derivatives*
Mannose / therapeutic use
Pancreatic Extracts / analysis
Prostaglandins / analysis
Rats
Rats, Inbred Strains
Tissue Distribution
para-Aminobenzoates

Substances

Aminobenzoates
Cyclosporins
Insulin
Pancreatic Extracts
Prostaglandins
para-Aminobenzoates
4-aminobenzoic acid-N-mannoside
Mannose
4-Aminobenzoic Acid