Pore dilation reconsidered

Nat Neurosci. 2015 Nov;18(11):1534-5. doi: 10.1038/nn.4148.

Abstract

Previous experiments have suggested that many P2X family channels undergo a time-dependent process of pore dilation when activated by ATP. Li et al. now propose a different interpretation of the key experiments.

Publication types

  • Comment

MeSH terms

  • Adenosine Triphosphate / pharmacology*
  • Humans
  • Ion Channel Gating / drug effects*
  • Membrane Potentials / drug effects*
  • Receptors, Purinergic P2X / metabolism*

Substances

  • Receptors, Purinergic P2X
  • Adenosine Triphosphate