Liquid biopsy: Clues on prostate cancer drug resistance

Michael T Schweizer; Emmanuel S Antonarakis

doi:10.1126/scitranslmed.aad4008

Liquid biopsy: Clues on prostate cancer drug resistance

Sci Transl Med. 2015 Nov 4;7(312):312fs45. doi: 10.1126/scitranslmed.aad4008.

Authors

Michael T Schweizer¹, Emmanuel S Antonarakis²

Affiliations

¹ Division of Oncology, Department of Medicine, University of Washington/Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. schweize@uw.edu eantona1@jhmi.edu.
² Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. schweize@uw.edu eantona1@jhmi.edu.

PMID: 26537254
DOI: 10.1126/scitranslmed.aad4008

Abstract

Analysis of tumor-derived cell-free DNA in blood yields insights into drug resistance in patients with castration-resistant prostate cancer (Romanel et al., this issue).

Publication types

Comment

MeSH terms

Drug Resistance, Neoplasm*
Humans
Male
Prostate-Specific Antigen / blood*
Prostatic Neoplasms, Castration-Resistant*
Receptors, Androgen*

Substances

Receptors, Androgen
Prostate-Specific Antigen