Identifying Novel Biomarkers in Sarcoidosis Using Genome-Based Approaches

Clin Chest Med. 2015 Dec;36(4):621-630. doi: 10.1016/j.ccm.2015.08.005. Epub 2015 Sep 26.

Abstract

This article briefly reviews conventional biomarkers used clinically to (1) support a diagnosis and (2) monitor disease progression in patients with sarcoidosis. Potential new biomarkers identified by genome-wide screening and the approaches to discover these biomarkers are described.

Keywords: Biomarkers; GWAS; Microarray; Molecular signature; Sarcoidosis; Sequencing.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Biomarkers / metabolism*
  • Genome-Wide Association Study / methods*
  • Humans
  • Sarcoidosis / diagnosis
  • Sarcoidosis / genetics*

Substances

  • Biomarkers