Intracranial dural based chondroma

Clemens Reinshagen; Navid Redjal; Dipti P Sajed; Brian V Nahed; Brian P Walcott

doi:10.1016/j.jocn.2015.05.052

Intracranial dural based chondroma

J Clin Neurosci. 2016 Mar:25:161-3. doi: 10.1016/j.jocn.2015.05.052. Epub 2015 Oct 24.

Authors

Clemens Reinshagen¹, Navid Redjal², Dipti P Sajed³, Brian V Nahed², Brian P Walcott⁴

Affiliations

¹ Molecular Neurotherapy and Imaging Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
² Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, White Building Room 502, Boston, MA 02114, USA.
³ Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
⁴ Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, White Building Room 502, Boston, MA 02114, USA. Electronic address: walcott.brian@mgh.harvard.edu.

PMID: 26602798
DOI: 10.1016/j.jocn.2015.05.052

Abstract

Intracranial chondromas are benign, slow-growing, cartilaginous tumors, which comprise only about 0.2% of all intracranial tumors. The majority of these lesions occur at the base of the skull, where they are thought to arise from residual embryonic chondrogenic cells along the basal synchondrosis. Very rarely, they may also originate from the convexity dura, falx cerebri, or the brain parenchyma. We present a patient with a dural based chondroma to highlight the technical considerations of surgical resection. The recent literature on intracranial chondromas regarding incidence, pathophysiologic origin, clinical symptoms, imaging, histopathology and prognosis is reviewed.

Keywords: Brain tumor; Chondroma; Histopathology; Surgery.

Publication types

Case Reports

MeSH terms

Adult
Brain Neoplasms / pathology*
Brain Neoplasms / surgery
Chondroma / pathology*
Chondroma / surgery
Dura Mater / pathology*
Female
Humans