Review of ultrasound appearance in inflammatory breast cancer: A pictorial essay

J Med Imaging Radiat Oncol. 2016 Feb;60(1):83-7. doi: 10.1111/1754-9485.12418. Epub 2015 Dec 2.

Abstract

Inflammatory breast cancer (IBC) is a rare malignancy accounting for 1-2% of breast cancers. It has an aggressive clinical presentation and poor prognosis. The sonographic findings in 41 patients with a clinical diagnosis of IBC and biopsy-proven breast malignancy are presented in this study. The most common finding was the presence of skin thickening (92%). Multiple small anechoic spaces within the dermis, correlating with the presence of dermal lymphatic invasion by tumour emboli on histopathology were noted in approximately one-third of cases. Other sonographic findings included single or multiple masses, parenchymal oedema, axillary lymphadenopathy, echogenic foci consistent with microcalcifications and increased vascularity.

Keywords: breast; dermal lymphatic dilatation; inflammatory breast cancer; skin thickening; ultrasound.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Female
  • Humans
  • Image Enhancement / methods
  • Inflammatory Breast Neoplasms / diagnostic imaging*
  • Observer Variation
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Ultrasonography, Mammary / methods*