Intraventricular Bone Wax as Cause of Recurrent Cerebrospinal Fluid Infection: A Neuroradiologic Pitfall

World Neurosurg. 2016 Apr:88:690.e7-690.e9. doi: 10.1016/j.wneu.2015.11.030. Epub 2015 Nov 30.

Abstract

Background: Persistent or recurrent shunt infections can be secondary to predisposing factors, such as isolated compartments, cerebrospinal fluid leaks, or foreign bodies.

Case description: A 5-year-old girl experienced several episodes of shunt infections. After careful reevaluation of all neuroradiologic records of the patient, a foreign body in the left frontal horn of the lateral ventricle was suspected. An endoscopic approach was used to identify and remove a small fragment of bone wax.

Conclusions: To our knowledge, this is the first report of intraventricular bone wax causing persistent CSF infection. The diagnosis was difficult because wax resembles air on computed tomography and on magnetic resonance imaging, and so it had been not noticed for months. Only its persistence on several images raised the suspicion of foreign body inside the ventricular system.

Keywords: Bone wax; CSF shunt infection; Choroid plexus coagulation; Endoscopic third ventriculostomy; Foreign body; Misdiagnosis.

Publication types

  • Case Reports

MeSH terms

  • Cerebrospinal Fluid / cytology
  • Cerebrospinal Fluid / microbiology*
  • Cerebrospinal Fluid Shunts / adverse effects
  • Child, Preschool
  • Diagnosis, Differential
  • Female
  • Foreign-Body Reaction / diagnosis*
  • Foreign-Body Reaction / etiology
  • Foreign-Body Reaction / microbiology
  • Humans
  • Infectious Encephalitis / diagnosis*
  • Infectious Encephalitis / etiology
  • Infectious Encephalitis / microbiology
  • Neuroimaging / methods
  • Palmitates / adverse effects*
  • Recurrence
  • Staphylococcal Infections / diagnosis*
  • Staphylococcal Infections / etiology*
  • Waxes / adverse effects*

Substances

  • Palmitates
  • Waxes
  • bone wax