In vivo targeting of leukemia stem cells by directing parthenolide-loaded nanoparticles to the bone marrow niche

Leukemia. 2016 Jul;30(7):1582-6. doi: 10.1038/leu.2015.343. Epub 2015 Dec 16.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antineoplastic Agents / administration & dosage*
  • Bone Marrow / drug effects
  • Cell Line, Tumor
  • Drug Delivery Systems / methods*
  • Humans
  • Leukemia, Myeloid, Acute*
  • Mice
  • Mice, Inbred NOD
  • Mice, SCID
  • Nanoparticles
  • Neoplastic Stem Cells / drug effects*
  • Sesquiterpenes / administration & dosage*
  • Stem Cell Niche / drug effects
  • Xenograft Model Antitumor Assays

Substances

  • Antineoplastic Agents
  • Sesquiterpenes
  • parthenolide