Mesothelial Cells Within Vascular Transformation of Mediastinal Lymph Node Sinuses: An Unusual Benign Collision Mimicking Colliding Malignancies

Int J Surg Pathol. 2016 Apr;24(2):121-3. doi: 10.1177/1066896915622277. Epub 2015 Dec 21.

Abstract

Vascular transformation of lymph node sinuses represents a rare benign entity mimicking malignant counterparts such as nodal Kaposi sarcoma. The presence of mildly atypical benign mesothelial cells within nodal sinuses raises the possibility of metastatic malignancy. Herein, a rare case of vascular transformation of lymph node sinuses with reactive sinusoidal mesothelial cells is outlined as a unique benign pathology and a potential mimicker of a malignant collision tumor.

Keywords: benign collision; lymph node; mesothelial cells; vascular transformation.

Publication types

  • Case Reports

MeSH terms

  • Biomarkers / analysis
  • Blood Vessels / pathology*
  • Carcinoma / pathology*
  • Diagnosis, Differential*
  • Epithelial Cells / pathology*
  • Humans
  • Immunohistochemistry
  • Incidental Findings
  • Lymph Nodes / pathology
  • Lymphatic Diseases / pathology*
  • Male
  • Mediastinum
  • Middle Aged

Substances

  • Biomarkers