Two Cases of Small Cell Lung Cancer Transformation from EGFR Mutant Adenocarcinoma During AZD9291 Treatment

J Thorac Oncol. 2016 Jan;11(1):e1-4. doi: 10.1016/j.jtho.2015.09.013.
No abstract available

Publication types

  • Case Reports
  • Clinical Trial, Phase I

MeSH terms

  • Acrylamides / therapeutic use*
  • Adenocarcinoma / drug therapy*
  • Adenocarcinoma / genetics
  • Adenocarcinoma / pathology
  • Aniline Compounds / therapeutic use*
  • Cell Transformation, Neoplastic / pathology*
  • ErbB Receptors / genetics*
  • Female
  • Humans
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / genetics
  • Lung Neoplasms / pathology
  • Middle Aged
  • Mutation / genetics*
  • Prognosis
  • Small Cell Lung Carcinoma / drug therapy*
  • Small Cell Lung Carcinoma / genetics
  • Small Cell Lung Carcinoma / pathology

Substances

  • Acrylamides
  • Aniline Compounds
  • osimertinib
  • EGFR protein, human
  • ErbB Receptors