Objective: To analyze risk factors for wound-specific complications after bulbar urethroplasty, including the association between incision type and complications.
Methods: This is a retrospective review of 829 urethroplasties excluding penile strictures, incomplete data sets, and radiation-induced urethral stenosis. Ninety-day wound complications were reported using the modified Clavien-Dindo classification of postoperative complications. Risk factors for wound complications were evaluated using univariable and multivariable analysis: patient age, positive preoperative urine culture, Charlson comorbidity index ≥ 2, diabetes, body mass index ≥ 35, smoking, and incision type (lambda perineal incision [LPI] vs. midline perineal incision [MPI]).
Results: Five hundred forty patients met inclusion criteria; 373 patients with an LPI and 167 patients with an MPI. Ninety-day wound complications (any Clavien grade) occurred in 21% of patients. Multivariable analyses indicated that incision type alone was significantly associated with wound complications (multivariable: MPI OR 0.53 (0.34-0.83), P = .01). The majority of complications were Clavien ≤ 2, which occurred in 23.3% (87 patients) of LPIs compared to 11.9% (20 patients) of MPIs (P = .002). The primary difference between the incisions was superficial wound edge separation (LPI 10.7% [40 patients]; MPI 0%, P < .0001). Early (6-month) urethroplasty success favored the midline incision (LPI 6.2% vs MPI 0%, P = .0003), implying no obvious technical advantage for the lambda incision. Study limitations include a retrospective design and the use of some patient-reported complication outcomes.
Conclusion: An LPI is independently associated with increased 90-day wound complications after urethroplasty, with no identifiable advantage in urethroplasty outcome.
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