Inv(8)(p23q22) and recombinant derivative in a Sicilian family

Clin Genet. 1989 Oct;36(4):256-61. doi: 10.1111/j.1399-0004.1989.tb03199.x.

Abstract

A family with inv8(p23q22), in which one girl with a derivative chromosome 8 showed the characteristic phenotype, is reported. Our case differs from the 32 known families with inv8(p23q22), being the first of apparently non-Hispanic descent. The anomaly may, however, have its origins in the Spanish domination of Sicily.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abnormalities, Multiple / genetics
  • Chromosome Inversion*
  • Chromosomes, Human, Pair 8*
  • Fathers
  • Female
  • Humans
  • Infant
  • Karyotyping
  • Recombination, Genetic*
  • Sicily