Impact of vaccination uptake on hospitalizations due to rotavirus acute gastroenteritis in 2 different socioeconomic areas of Spain

Hum Vaccin Immunother. 2016 Apr 2;12(4):1035-9. doi: 10.1080/21645515.2015.1118592.

Abstract

Rotavirus is the leading cause of hospitalization due to acute gastroenteritis (AGE) in infants and toddlers. However, rotavirus vaccination has been associated with a decline in hospitalization rates due to rotavirus AGE. A descriptive retrospective study was conducted to analyze the impact of rotavirus vaccination on the rate of hospitalizations due to AGE among children ≤2 years old in 2 areas of the province of Almería, Spain. After eight years of rotavirus vaccination, rates of hospitalizations due to rotavirus AGE are diminished. This decline is closely related to vaccine coverage in the studied areas.

Keywords: acute gastroenteritis; coverage; diarrhea; hospitalization; rotavirus; uptake; vaccine.

MeSH terms

  • Acute Disease / epidemiology
  • Child, Preschool
  • Diarrhea / prevention & control
  • Diarrhea / virology
  • Enterovirus Infections / prevention & control
  • Female
  • Gastroenteritis / epidemiology
  • Gastroenteritis / prevention & control*
  • Gastroenteritis / virology
  • Hospitalization / statistics & numerical data*
  • Humans
  • Infant
  • Male
  • Regression Analysis
  • Retrospective Studies
  • Rotavirus / immunology
  • Rotavirus Infections / epidemiology
  • Rotavirus Infections / prevention & control*
  • Rotavirus Infections / virology
  • Rotavirus Vaccines / administration & dosage*
  • Rotavirus Vaccines / adverse effects
  • Socioeconomic Factors*
  • Spain / epidemiology
  • Vaccination

Substances

  • Rotavirus Vaccines