Description of a novel HLA-DQB1 allele, HLA-DQB1*06:126, in the Saudi stem cell donor registry

HLA. 2016 Jan;87(1):58-9. doi: 10.1111/tan.12703. Epub 2015 Nov 24.

Abstract

HLA-DQB1*06:126 differs from HLA-DQB1*06:02:01 by a nonsynonymous C to T substitution at nucleotide position 1621 in Exon 2.

Keywords: HLA‐DQB1*06:126; Saudi stem cell donor registry; sequence‐based typing.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles*
  • Amino Acid Sequence
  • Amino Acid Substitution
  • Base Sequence
  • Codon
  • Exons
  • Gene Expression
  • Genetic Loci
  • HLA-DQ beta-Chains / genetics*
  • HLA-DQ beta-Chains / immunology
  • Hematopoietic Stem Cell Transplantation
  • Hematopoietic Stem Cells / cytology
  • Hematopoietic Stem Cells / immunology*
  • Histocompatibility Testing
  • Humans
  • Molecular Sequence Data
  • Polymorphism, Single Nucleotide*
  • Registries*
  • Saudi Arabia
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Tissue Donors

Substances

  • Codon
  • HLA-DQ beta-Chains
  • HLA-DQB1 antigen