Presurgical Mapping of the Language Network Using Resting-state Functional Connectivity

Top Magn Reson Imaging. 2016 Feb;25(1):19-24. doi: 10.1097/RMR.0000000000000073.

Abstract

Resting-state functional magnetic resonance imaging (resting-state fMRI) is a tool for investigating the functional networks that arise during the resting state of the brain. Recent advances of the resting-state fMRI analysis suggest its feasibility for evaluating language function. The most common clinical application is for presurgical mapping of cortex for a brain tumor or for resective epilespy surgery. In this article, we review the techniques and presurgical applications of resting-state fMRI analysis for language evaluation, and discuss the use in the clinical setting, focusing on planning for neurosurgery.

Publication types

  • Review

MeSH terms

  • Cerebral Cortex / physiopathology*
  • Cerebral Cortex / surgery
  • Connectome / methods
  • Electric Stimulation / methods*
  • Epilepsy / diagnosis*
  • Epilepsy / physiopathology
  • Epilepsy / surgery*
  • Humans
  • Intraoperative Neurophysiological Monitoring / methods
  • Language*
  • Magnetic Resonance Imaging / methods*
  • Preoperative Care / methods
  • Rest