Primary angiosarcoma of the breast

Daniele Bordoni; Elisa Bolletta; Giuseppe Falco; Pierfrancesco Cadenelli; Nicola Rocco; Ariel Tessone; Stefania Guarino; Antonello Accurso; Bruno Amato; Cesare Magalotti

doi:10.1016/j.ijscr.2016.02.003

Primary angiosarcoma of the breast

Int J Surg Case Rep. 2016;20S(Suppl):12-5. doi: 10.1016/j.ijscr.2016.02.003. Epub 2016 Feb 3.

Authors

Affiliations

¹ Department of Senology, Asur Marche Area Vasta 1, Santa Maria della Misericordia, Via Comandino 70, Urbino, Italy. Electronic address: Daniele.bordoni@sanita.marche.it.
² Department of Plastic and Reconstructive Surgery, University of Ancona, Via Conca 71, Ancona, Italy. Electronic address: Elisa.bolletta.md@gmail.com.
³ Breast Surgery Unit, IRCCS-Arcispedale Santa Maria Nuova, Viale Risorgimento 80, 42123 Reggio Emilia, Italy. Electronic address: giuseppe.falco@asmn.re.it.
⁴ Department of Plastic Surgery, Hand Surgery and Microsurgery, San Gerardo Hospital, Monza, Milano, Italy. Electronic address: p.cadenelli@hotmail.it.
⁵ Department of Clinical Medicine and Surgery. University of Naples "Federico II", Naples, Italy. Electronic address: nicolarocco2003@gmail.com.
⁶ Department of Plastic and Reconstructive Surgery, The Talpiot Medical Leadership Program, Sheba Medical Center, Israel. Electronic address: arieltessonemd@me.com.
⁷ Department of Oncology, Asur Marche Area Vasta 1, Santa Maria della Misericordia, Via Comandino 70, Urbino, Italy. Electronic address: guarino@sanita.marche.it.
⁸ Department of Gastroenterology, Endocrinology and Surgery, AO "Federico II", Naples, Italy. Electronic address: antonello.accurso@unina.it.
⁹ Department of Clinical Medicine and Surgery. University of Naples "Federico II", Naples, Italy. Electronic address: bramato@unina.it.

Abstract

Primary angiosarcoma (AS) of the breast is a rare neoplasia that is not related to radiation exposure. It represents less than 0.05% of all malignant breast tumors. This lesion is characterized by aggressive patterns and poor prognosis and by the absence of typical features at radiologic examination. Currently there are not evidence-based guidelines regarding surgical and adjuvant treatment for this tumor even though wide surgical resection followed by chemo- radiotherapy appears to improve both disease free survival and overall survival. The aim of this study was to analyze the available series of AS patients suggesting the most reliable treatment options for this rare neoplasia.

Keywords: Angiosarcoma; Breast cancer; Breast sarcomas.