PLK1shRNA and doxorubicin co-loaded thermosensitive PLGA-PEG-PLGA hydrogels for localized and combined treatment of human osteosarcoma

Affiliations

• ¹ Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China. Electronic address: clhe@ciac.ac.cn.
• ² Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China; Department of Orthopaedics, The First Hospital of Jilin University, Jilin University, Changchun 130021, China.
• ³ Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
• ⁴ Department of Orthopaedics, The First Hospital of Jilin University, Jilin University, Changchun 130021, China.
• ⁵ Department of Orthopaedics, The First Hospital of Jilin University, Jilin University, Changchun 130021, China. Electronic address: jgliu.2005@aliyun.com.
• ⁶ Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China. Electronic address: thy@ciac.ac.cn.