Multidrug-resistant Combined Infections in a Liver Transplanted Patient: Case Report

Exp Clin Transplant. 2018 Jun;16(3):340-343. doi: 10.6002/ect.2015.0312. Epub 2016 Apr 7.

Abstract

We report a case of successfully treated multiple liver abscesses in a liver-transplanted patient, sustained by combined multidrug-resistant infections. Two months after a liver transplant, a computed tomography scan revealed the presence of multiple abscesses in the liver graft. Blood cultures and abscessual liver fluid were both positive for acquired colistin- and carbapenem- resistant Klebsiella pneumoniae and an extended-spectrum of beta-lactamases-producing Enterobacter aerogenes. The treatment strategy consisted of different prolonged antimicrobial combinations and draining of the abscesses with complete recovery of the liver lesions.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / administration & dosage*
  • Coinfection*
  • Drainage
  • Drug Resistance, Multiple, Bacterial*
  • Drug Therapy, Combination
  • Enterobacter aerogenes / drug effects*
  • Enterobacter aerogenes / isolation & purification
  • Enterobacteriaceae Infections / diagnosis
  • Enterobacteriaceae Infections / drug therapy*
  • Enterobacteriaceae Infections / microbiology
  • Female
  • Humans
  • Klebsiella Infections / diagnosis
  • Klebsiella Infections / drug therapy*
  • Klebsiella Infections / microbiology
  • Klebsiella pneumoniae / drug effects*
  • Klebsiella pneumoniae / isolation & purification
  • Liver Abscess / diagnosis
  • Liver Abscess / drug therapy*
  • Liver Abscess / microbiology
  • Liver Transplantation / adverse effects*
  • Microbial Sensitivity Tests
  • Positron Emission Tomography Computed Tomography
  • Time Factors
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents