Incidental Finding of a Neuroendocrine Tumor Arising from Meckel Diverticulum During Hernia Repair - A Case Report and Literature Review

Anticancer Res. 2016 Apr;36(4):1861-4.

Abstract

Meckel diverticulum is the most common abnormality of the gastrointestinal tract arising from an incomplete obliteration of the vitelline duct during the intrauterine life. Although tumor development in Meckel diverticulum is not a common situation, it can occur due to the persistence of cellular islets with gastric, pancreatic or intestinal origin. The presence of a neuroendocrine tumor arising from Meckel diverticulum is even scarcer. We present the case of a 59-year-old patient in whom a Meckel diverticulum was found during surgery for inguinal hernia; the histopathological and immunohistochemical studies revealed the presence of a well-differentiated neuroendocrine tumor with low mitotic index.

Keywords: Hernia; Meckel diverticulum; neuroendocrine tumor.

Publication types

  • Case Reports

MeSH terms

  • Chromogranin A / metabolism
  • Hernia, Inguinal / surgery*
  • Herniorrhaphy
  • Humans
  • Incidental Findings
  • Ki-67 Antigen / metabolism
  • Meckel Diverticulum / complications*
  • Meckel Diverticulum / pathology
  • Middle Aged
  • Neuroendocrine Tumors / etiology*
  • Neuroendocrine Tumors / metabolism
  • Neuroendocrine Tumors / pathology
  • Receptors, Somatostatin / metabolism
  • Synaptophysin / metabolism

Substances

  • Chromogranin A
  • Ki-67 Antigen
  • Receptors, Somatostatin
  • SSTR2 protein, human
  • Synaptophysin
  • somatostatin receptor 5