Cerebral syphilitic gumma is extremely rare and easily misdiagnosed. We illustrate a case of a cerebral syphilitic gumma developed in just a few months mimicking a brain tumor in a HIV-negative patient and Treponema pallidum was detected in the cerebral syphilitic gumma.
Keywords: Biopsy; Treponema pallidum; cerebral syphilitic gumma; differential diagnosis; infection; inflammation.