Fatal GvHD induced by PD-1 inhibitor pembrolizumab in a patient with Hodgkin's lymphoma

Bone Marrow Transplant. 2016 Sep;51(9):1268-70. doi: 10.1038/bmt.2016.111. Epub 2016 Apr 25.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Antibodies, Monoclonal, Humanized / adverse effects*
  • Fatal Outcome
  • Graft vs Host Disease / chemically induced*
  • Graft vs Host Disease / etiology
  • Hematopoietic Stem Cell Transplantation / adverse effects
  • Hodgkin Disease / complications
  • Hodgkin Disease / therapy
  • Humans
  • Male
  • Pneumonia
  • Programmed Cell Death 1 Receptor / antagonists & inhibitors
  • Transplantation, Autologous

Substances

  • Antibodies, Monoclonal, Humanized
  • PDCD1 protein, human
  • Programmed Cell Death 1 Receptor
  • pembrolizumab