Chondrocyte unresponsiveness to insulin-like growth factor-1. A novel pathogenetic mechanisms for cartilage destruction in experimental arthritis

Agents Actions. 1989 Jan;26(1-2):193-5. doi: 10.1007/BF02126606.
No abstract available

MeSH terms

  • Animals
  • Arthritis / metabolism*
  • Arthritis, Experimental / metabolism*
  • Arthritis, Experimental / pathology
  • Cartilage, Articular / drug effects*
  • Cartilage, Articular / metabolism
  • Cartilage, Articular / pathology
  • Insulin-Like Growth Factor I / pharmacology*
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Proteoglycans / biosynthesis
  • Recombinant Proteins / pharmacology
  • Somatomedins / pharmacology*
  • Zymosan / toxicity

Substances

  • Proteoglycans
  • Recombinant Proteins
  • Somatomedins
  • Insulin-Like Growth Factor I
  • Zymosan