First Report of a Verona Integron-Encoded Metallo-β-Lactamase-Producing Klebsiella pneumoniae Infection in a Child in the United States

J Pediatric Infect Dis Soc. 2016 Sep;5(3):e24-7. doi: 10.1093/jpids/piw025. Epub 2016 May 4.

Abstract

We report the first case of a child in the United States infected with an organism producing a Verona Integron-Encoded Metallo-β-Lactamase. This child succumbed to a ventilator-associated pneumonia caused by a Klebsiella pneumoniae producing this resistance mechanism.

Keywords: CRE; VIM; carbapenemase; metallo-β-lactamase; pediatrics.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Drug Resistance, Bacterial
  • Fatal Outcome
  • Humans
  • Integrons
  • Klebsiella Infections / diagnosis*
  • Klebsiella Infections / microbiology*
  • Klebsiella pneumoniae / drug effects
  • Klebsiella pneumoniae / enzymology
  • Klebsiella pneumoniae / genetics
  • Klebsiella pneumoniae / isolation & purification*
  • Male
  • Pneumonia, Ventilator-Associated / diagnosis*
  • Pneumonia, Ventilator-Associated / microbiology*
  • United States
  • beta-Lactamases / metabolism

Substances

  • beta-Lactamases